Project

Transfer of miRNA from single HDL particles to cells

Project

May 2016 - May 2019
In cooperation with the Medical University of Vienna and the University of New South Wales in Sydney, high-resolution microscopy techniques are used to characterize nanolevel microRNA communication between tissues within the body.

Research program

FWF Translational Research


Das Projekt wird im Translational Research Programm durch den FWF Wissenschaftsfonds gefördert.

2019
B. Plochberger, H. Stangl, A. Karner, M. Axmann, S. M. Meier - Enrichment of Native Lipoprotein Particles with microRNA and Subsequent Determination of Their Absolute/Relative microRNA Content and Their Cellular Transfer Rate - Enrichment of Native Lipoprotein Particles with microRNA ans Subsequent Determination… more
2019
M. Axmann, E. Sezgin, A. Karner, J. Novacek, M. Brodesser, C. Röhrl, J. Preiner, H. Stangl, B. Plochberger - Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes - Nano Letters , Vol. 19, No. 4, 2019, pp. 2562-2567 more
2018
B. Plochberger, M. Axmann, E. Sezgin, J. Preiner, A. Karner, C. Röhrl, M. Brodesser, C. Eggeling, G. Schütz, H. Stangl - Direct Visualization of Lipoprotein Mediated Cholesterol Transport at the Phospholipid Bilayer Interface - BIOPHYSICAL JOURNAL, Vol. 114, No. 3, 2018 more
2018
A. Karner, M. Axmann, J. Preiner, E. Sezgin, M. Brodesser, C. Röhrl, C. Eggeling, H. Stangl, B. Plochberger - Direct visualization of LDL-mediated cholesterol transport at the phospholipid bilayer interface - XX. Annual Linz Winter Workshop 2018, Linz, Austria, 2018 more
2018
B. Plochberger, M. Axmann, C. Röhrl, J. Weghuber, M. Brameshuber, S. Mayr, R. Ros, R. Bittman, H. Stangl, G. Schütz - Direct observation of cargo transfer from HDL particles to the plasma membrane - ATHEROSCLEROSIS, 2018, pp. 53-59 more
2018
M. Axmann, S. M. Meier, A. Karner, W. Strobl, H. Stangl, B. Plochberger - Serum and Lipoprotein Particle miRNA Profile in Uremia Patients - Genes, 2018, pp. 17 more
2017
H. Stangl, B. Plochberger - How little snippets calcify the arteries - Der Standard, 2017 more
2017
B. Plochberger, C. Röhrl, J. Preiner, C. Rankl, M. Brameshuber, E. Sezgin, P. Hinterdorfer, H. Stangl, G. Schütz, R. Ros, J. Madl, C. Eggeling - HDL particles incorporate into lipid bilayers – a combined AFM and single molecule fluorescence microscopy study - Scientific Reports, Vol. 7, No. 15886,… more
2016
B. Plochberger, C. Röhrl, H. Stangl, J. Preiner, P. Hinterdorfer, G. Schütz, J. Weghuber, E. Sezgin - Receptor-Mediated HDL-Lipid Uptake is Regulated by Elastic Properties of the Plasma Membrane - BIOPHYSICAL JOURNAL, Vol. 110, No. 3, 2016 more
2016
B. Plochberger, R. Wollhofen, J. Jacak, M. Axmann, G. Schütz, T. Klar - Confinement of Lipid Membranes by Nanostructured Polymer Patterns for Cell to Cell Mimicking - BIOPHYSICAL JOURNAL, Vol. 110, No. 3, 2016 more