Faculty

Bioinformatics Research Group

In bioinformatics, researchers at FH OÖ support specialists in life sciences, such as doctors, biologists and geneticists, with intelligent software systems for analysis of molecular biological data and for the simulation of biological processes.

In general, bioinformatics is that branch of computer science, whose goal is to create a basis for the management and integration of biological data and develop a variety of analyzes for these specific data. We are researching and developing algorithmic approaches for genomics, for the sequence analysis for proteomics (the study of the proteome), for structural biology, and last but not least the application of machine learning methods in the analysis of biological data.
2019
S. Dorl, S. M. Winkler, K. Mechtler, V. Dorfer - MS Ana: A spectral library search engine optimized for high-accuracy fragment ion data - Proceedings of the 2019 EuBIC Winter School on proteomics bioinformatics, Zakopane, Poland, 2019 more
2018
S. Willems, D. Bouyssie, D. Deforce, V. Dorfer, V. Gorshkov, D. Kopczynski, K. Laukens, M. Locard-Paulet, V. Schwämmle, J. Uszkoreit, D. Valkenborg, M. Vaudel, W. Bittremieux - Proceedings of the EuBIC developer's meeting 2018 - Journal of Proteomics, 2018, pp. 25-27 more
2018
V. Dorfer, S. Maltsev, S. M. Winkler, K. Mechtler - CharmeRT: Boosting Peptide Identifications by Chimeric Spectra Identification and Retention Time Prediction - Journal of Proteome Research, 2018, pp. 2581-2589 more
2018
E. W. Deutsch, Y. Perez-Riverol, R. J. Chalkley, M. Wilhelm, S. Tate, T. Sachsenberg, M. Walzer, L. Käll, B. Delanghe, S. Böcker, E. L. Schymanski, P. Wilmes, V. Dorfer, B. Küster, P. Volders, N. Jehmlich, J. Vissers, D. W. Wolan, A. Y. Wang, L. Mendoza, J. Shofstahl, A. W. Dowsey, J. Griss, R. Salek,… more
2017
S. Dorl, S. M. Winkler, K. Mechtler, V. Dorfer - Identifying tandem mass spectra of phosphorylated peptides before database search using machine-learning - Proceedings of the 2017 EuBIC Winter School on proteomics bioinformatics, Semmering, Austria, 2017 more
2017
K. Pröll - DEEP LEARNING APPROACHES FOR SMALL DIMENSIONAL BIOMEDICAL DATA - Proceedings of the 29th European Modeling and Simulation Symposium EMSS 2017, Barcelona, Spain, 2017, pp. 176-180 more
2017
S. Dorl, S. M. Winkler, K. Mechtler, V. Dorfer - PhoStar: Identifying Tandem Mass Spectra of Phosphorylated Peptides before Database Search - Journal of Proteome Research, 2017 more
2016
S. Dorl, S. M. Winkler, K. Mechtler, V. Dorfer - Identifying tandem mass spectra of phosphorylated peptides before database search using machine-learning - Proceedings of the Austrian Proteomics Research Symposium (APRS2016), Wien, Austria, 2016 more
2016
D. M. Borgmann, S. Mayr, H. Polin, S. Schaller, V. Dorfer, L. Obritzberger, T. Endmayr, C. Gabriel, S. M. Winkler, J. Jacak - Single Molecule Fluorescence Microscopy and Machine Learning for Rhesus D Antigen Classification - Scientific Reports, Vol. 6, No. 32317, 2016 more
2015
V. Dorfer, S. Maltsev, S. Dreiseitl, K. Mechtler, S. M. Winkler - A Symbolic Regression Based Scoring System Improving Peptide Identifications for MS Amanda - Proceedings of the 11th GECCO Workshop on Medical Applications of Genetic and Evolutionary Computation MedGEC, Madrid, Spain, 2015 more
2015
S. Schaller, J. Weinberger, R. Jimenez-Heredia, M. Danzer, R. Oberbauer, C. Gabriel, S. M. Winkler - ImmunExplorer (IMEX): a software framework for diversity and clonality analyses of immunoglobulins and T cell receptors on the basis of IMGT/HighV-QUEST preprocessed NGS data - BMC Bioinformatics, Vol.… more
2015
M. Danzer, J. Weinberger, R. Jimenez-Heredia, S. Schaller, S. Süssner, S. M. Winkler, J. Sunzenauer, R. Oberbauer, H. Steitzer, C. Gabriel - Profiling the T- and B-cell receptor repertoire of a patient with acute kidney rejection by high-throughput sequencing - Proceedings of the 29th European Immunogenetics… more
2015
V. Dorfer, S. Maltsev, S. M. Winkler, K. Mechtler - Chimeric MS/MS Spectra Identification using MS Amanda - Proceedings of 63rd ASMS Conference on Mass Spectrometry and Allied Topics (ASMS 2015), St. Louis, United States of America, 2015 more
2015
J. Jacak, S. Schaller, D. M. Borgmann, S. M. Winkler - Characterization of the Distance Relationship Between Localized Serotonin Receptors and Glia Cells on Fluorescence Microscopy Images of Brain Tissue - MICROSCOPY AND MICROANALYSIS, Vol. 21, No. 4, 2015 more
2015
S. Schaller, J. Weinberger, M. Danzer, S. M. Winkler - Detailed Analysis of Clonality, Diversity, and Gene Frequency Distributions in B- & T-Cell Receptors based on NGS Data - Proceedings of the VIB Conference Series: Revolutionizing Next-Generation Sequencing: Tools and Technologies, Leuven, Belgium,… more
2015
S. Schaller, J. Weinberger, R. Jimenez-Heredia, M. Danzer, S. M. Winkler - ImmunExplorer (IMEX): A detailed analysis of the health status of the immune system using NGS immunoglobulin and T cell receptor IMGT/HighV-QUEST data - 4th European Congress of Immunology, Vienna, Austria, 2015 more
2015
S. Schaller, J. Weinberger, M. Danzer, S. M. Winkler - Modelling States of Human Adaptive Immune Systems by Analyzing B- and T-Cell Receptors using Machine Learning - Lecture Notes in Computer Science LNCS 9520, Las Palmas, Gran Canaria, Spain, 2015 more
2014
V. Dorfer, G. Dürnberger, S. M. Winkler, K. Mechtler - Searching Chimeric MS/MS Spectra with MS Amanda - Proceedings of the 12th Austrian Proteomic Research Symposium (APRS 2014), Salzburg, Austria, 2014 more
2014
V. Dorfer, P. Pichler, T. Stranzl, J. Stadlmann, T. Taus, S. M. Winkler, K. Mechtler - MS Amanda, a Universal Identification Algorithm Optimized for High Accuracy Tandem Mass Spectra - Journal of Proteome Research, Vol. 13, No. 8, 2014, pp. 3679-3684 more
2014
S. Schaller, J. Weinberger, M. Danzer, S. M. Winkler - ImmunExplorer: A Framework for NGS-based Characterization and Visualization of the Human Immune System - Proceedings of the 22nd Annual International Conference on Intelligent Systems for Molecular Biology (ISMB), Boston, United States of America,… more
2014
V. Dorfer, P. Pichler, T. Stranzl, G. Dürnberger, S. M. Winkler, K. Mechtler - A Standalone Version of MS Amanda for Integration into Proteomics Workflows - Proceedings of the 13th Human Proteome Organization World Congress (HUPO 2014), Madrid, Spain, 2014 more
2014
L. Obritzberger, S. Schaller, V. Dorfer, C. Loimayr, S. Hennerbichler, S. M. Winkler - Identification of Endothelial Cell Morphology in Cornea Using Evolution Strategies - Proceedings of the 26th European Modeling and Simulation Symposium EMSS 2014, Bordeaux, France, 2014 more
2014
S. M. Winkler, M. Affenzeller, G. K. Kronberger, M. Kommenda, S. Wagner, W. Jacak, H. Stekel - On the Identification of Virtual Tumor Markers and Tumor Diagnosis Predictors Using Evolutionary Algorithms in Advanced Methods and Applications in Computational Intelligence (Editors: R. Klempous, J. Nikodem,… more
2014
J. Weinberger, R. Jimenez-Heredia, S. Schaller, M. Danzer, J. Sunzenauer, S. Süssner, H. Polin, S. M. Winkler, R. Oberbauer, C. Gabriel - Next-generation sequencing based receptor repertoire analysis reveals that expanded B- and T-cells can be found in renal tissue as well as in peripheral blood - Proceedings… more
2014
V. Dorfer, P. Pichler, T. Stranzl, S. M. Winkler, K. Mechtler - MS Amanda Stand-Alone for Integration in Proteomics Workflows - Proceedings of 62rd ASMS Conference on Mass Spectrometry and Allied Topics (ASMS 2014), Baltimore, United States of America, 2014 more
2014
S. Schaller, J. Weinberger, M. Danzer, C. Gabriel, R. Oberbauer, S. M. Winkler - Mathematical Modeling of the Diversity in Human B and T Cell Receptors using Machine Learning - Proceedings of the 26th European Modeling and Simulation Symposium EMSS 2014, Bordeaux, France, 2014 more
2013
J. Jacak, S. Schaller, M. Sams, D. M. Borgmann, R. Silye, S. M. Winkler - Spatial Analysis Approach for the Classification of Localization Microscopy Images - Linz Winter School 2013, Linz, Austria, 2013 more
2013
V. Dorfer, P. Pichler, S. M. Winkler, K. Mechtler - MS Amanda: A Novel Algorithm for the Identification of High Accuracy Tandem Mass Spectrometry Data - Proceedings of 11th Austrian Proteomic Research Symposium (APRS 2013), Innsbruck, Austria, 2013 more
2013
S. M. Winkler, M. Affenzeller, H. Stekel - An Integrated Clustering an Classification Approach for the Analysis of Tumor Patient Data - Lecture Notes in Computer Science LNCS 8111, Las Palmas de Gran Canaria, Spain, 2013, pp. 230-233 more
2013
S. Schaller, J. Jacak, D. Gschwandtner, P. Bettelheim, S. M. Winkler - Identification of PNH Affected Cells by Classifying Motion Characteristics of Single Molecules - Proceedings of the International Workshop on Innovative Simulation for Health Care (IWISH), Athen, Greece, 2013, pp. 52-57 more
2013
V. Dorfer, P. Pichler, S. M. Winkler, K. Mechtler - MS Amanda: A Novel Algorithm for the Identification of High Accuracy Tandem Mass Spectrometry Data - 61st ASMS Conference on Mass Spectrometry and Allied Topics, Minneapolis, United States of America, 2013 more
2013
S. Schaller, J. Jacak, M. Sams, S. M. Winkler - Statistical Analysis of the Relationship between Spots and Structures in Microscopy Images - Lecture Notes in Computer Science LNCS 8111, Las Palmas de Gran Canaria, Spain, 2013 more
2013
S. M. Winkler, M. Affenzeller, H. Stekel - Evolutionary Identification of Cancer Predictors Using Clustered Data - Companion Publication of the 2013 Genetic and Evolutionary Computation Conference, GECCO'13 Companion, Amsterdam, Netherlands, 2013, pp. 1463-1470 more
2013
S. Schaller, J. Jacak, P. Bettelheim, D. Gschwandtner, S. M. Winkler - Analyzing Motion Characteristics of Single Molecules for Providing Evidence of PNH in Microscopy Images - Proceedings of the 21st Annual International Conference on Intelligent Systems for Molecular Biology (ISMB), Berlin, Germany,… more
2013
R. Rid, W. Strasser, D. Siegl, C. Frech, M. Kommenda, T. Kern, H. Hintner, J. W. Bauer, K. Oender - PRIMOS: An Integrated Database of Reassessed Protein–Protein Interactions Providing Web-Based Access to In Silico Validation of Experimentally Derived Data - ASSAY and Drug Development Technologies,… more
2012
S. M. Winkler, M. Affenzeller, W. Jacak, H. Stekel - Data Based Prediction of Tumor Diagnoses and the Role of Tumor Markers - Proceedings of the 20th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB), Long Beach, CA, United States of America, 2012 more
2012
S. Schaller, S. M. Winkler, J. Weghuber, M. Sams, J. Jacak - µDetect: Design of a Framework for Optimized Structure Analysis in Fluorescence Microscopy Images - Proceedings of 6th FFH 2012, Graz, Austria, 2012, pp. 125-129 more
2012
S. M. Winkler, M. Affenzeller, H. Stekel - Analysis of the Relevance of Blood Parameters and Virtual Tumor Markers in Tumor Diagnosis Prediction - Proceedings of IEEE APCAST'12 Conference, Sydney, Australia, 2012 more
2012
S. M. Winkler, M. Affenzeller, G. K. Kronberger, M. Kommenda, S. Wagner, W. Jacak, H. Stekel - Analysis of Selected Evolutionary Algorithms in Feature Selection and Parameter Optimization for Data Based Tumor Marker Modeling - LECTURE NOTES IN COMPUTER SCIENCE, Vol. 6927, No. 1, 2012, pp. 335-342 more
2012
V. Dorfer, P. Pichler, S. M. Winkler, K. Mechtler - Identifying HCD & ETD Spectra – A New Approach - Proceedings of the 10th Austrian Proteomic Research Symposium, Graz, Austria, 2012 more
2012
S. M. Winkler, M. Affenzeller, G. K. Kronberger, M. Kommenda, S. Wagner, W. Jacak, H. Stekel - Variable Interaction Networks in Medical Data - Proceedings of the 24th European Modeling and Simulation Symposium EMSS 2012, Vienna, Austria, 2012, pp. 265-270 more
2011
H. Brandstätter-Müller, B. Parsapour, A. Hoelzlwimmer, G. Lirk, P. Kulczycki - Improving Job Scheduling on a Heterogeneous Cluster by Predicting Job Execution Times Using Heuristics - Proccedings of 23rd IEEE European Modeling & Simulation Symposium EMSS 2011, Roma, Italy, 2011, pp. 488-495 more
2011
S. M. Winkler, M. Affenzeller, G. K. Kronberger, M. Kommenda, S. Wagner, W. Jacak, H. Stekel - On the Use of Estimated Tumor Marker Classifications in Tumor Diagnosis Prediction - A Case Study for Breast Cancer - Proccedings of 23rd IEEE European Modeling & Simulation Symposium EMSS 2011, Roma, Italy,… more
2011
V. Dorfer, S. M. Winkler, T. Kern, S. Blank, G. Petz, P. Faschang - Keyword Clustering in Biomedical Information Retrieval Using Evolutionary Algorithms - Proceedings of the 19th Annual International Conference on Intelligent Systems for Molecular Biology and 10th European Conference on Computational… more
2011
S. M. Winkler, M. Affenzeller, W. Jacak, H. Stekel - Identification of Cancer Diagnosis Estimation Models Using Evolutionary Algorithms - A Case Study for Breast Cancer, Melanoma, and Cancer in the Respiratory System - Proceedings of the Genetic and Evolutionary Computation Conference GECCO 2011, Dublin,… more
2011
S. M. Winkler, M. Affenzeller, G. K. Kronberger, M. Kommenda, S. Wagner, W. Jacak, H. Stekel - Analysis of Selected Evolutionary Algorithms in Feature Selection and Parameter Optimization for Data Based Tumor Marker Modeling - Proceedings of International Conference on Computer Aided Systems Theory EUROCAST… more
2011
M. Affenzeller, S. M. Winkler, W. Jacak, H. Stekel - Cancer Prediction Models Based on Blood Data with and without Tumor Marker Information - Symposium 2011 of the German, Austrian, and Swiss Societies for Hematology and Onkology, Basel, Germany, 2011 more
2011
S. M. Winkler, M. Affenzeller, W. Jacak, H. Stekel - Data Based Prediction of Classification of Tumor Markers AFP, CA-125, CA15-3, CEA, CYFRA, and PSA. - Journal of Clinical Chemistry and Laboratory Medicine, Berlin, Germany, 2011 more
2011
V. Dorfer, S. M. Winkler, T. Kern, S. Blank, G. Petz, P. Faschang - On the Performance of Evolutionary Algorithms in Biomedical Keyword Clustering - Proceedings of the Genetic and Evolutionary Computation Conference GECCO 2011, Dublin, Ireland, 2011 more
2011
B. Parsapour, H. Brandstaetter-Mueller, A. Hoelzlwimmer, G. Lirk, P. Kulczycki - Performant Calculation of DNA-Primers via GPGPUs - Proceedings of the fifth Research Forum of the Austrian University of Applied Sciences, Wien (Favoriten), Austria, 2011, pp. 2 more
2011
V. Dorfer, S. M. Winkler, T. Kern, G. Petz, P. Faschang - Analysis of Single-Objective and Multi-Objective Evolutionary Algorithms in Keyword Cluster Optimization - Proceedings of International Conference on Computer Aided Systems Theory EUROCAST 2011, Las Palmas, Spain, 2011, pp. 3 more
2011
S. M. Winkler, M. Affenzeller, W. Jacak, H. Stekel - Heuristic Tumor Markers - Data Based Identification of Classification Models for Tumor Markers. - Symposium 2011 of the German, Austrian, and Swiss Societies for Hematology and Onkology, Basel, Germany, 2011 more
2011
S. M. Winkler, M. Affenzeller, H. Stekel - Genetic Programming for the Data Based Generation of Medical Diagnosis Models. - Journal of Clinical Chemistry and Laboratory Medicine, Berlin, Germany, 2011 more
2011
S. M. Winkler, M. Affenzeller, G. K. Kronberger, M. Kommenda, S. Wagner, W. Jacak, H. Stekel - Data Based Identification of Estimation Models for Tumor Markers Using Evolutionary Computation - Proceedings of the 19th Annual International Conference on Intelligent Systems for Molecular Biology and 10th… more
2010
H. Brandstaetter-Mueller, A. Hoelzlwimmer, B. Parsapour, G. Lirk, P. Kulczycki - An Application Framework for the Scheduling of HPC Jobs on Hybrid Hardware Platforms for Solving Bioinformatical Problems - 55th GMDS Congress, Mannheim, Germany, 2010, pp. 354-355 more
2010
S. M. Winkler, M. Affenzeller, W. Jacak, H. Stekel - Classification of Tumor Marker Values Using Heuristic Data Mining Methods - Proceedings of the Genetic and Evolutionary Computation Conference GECCO 2010, Portland, United States of America, 2010, pp. 8 more
2010
S. M. Winkler - Structural Versus Evaluation Based Solutions Similarity in Genetic Programming Based System Identification - Proceedings of the 2010 Workshop on Nature Inspired Cooperative Strategies for Optimization (NICSO 2010), Granada, Spain, 2010 more
2010
C. Fischer, L. Bloder, C. Neumüller, S. Pimminger, M. Affenzeller, S. M. Winkler, H. Stekel, R. Frechinger - Prediction of Blood Demands in a Hospital - 22nd European Modeling and Simulation Symposium EMSS 2010, Fes, Morocco, 2010, pp. 6 more
2010
V. Dorfer, S. M. Winkler, T. Kern, G. Petz, P. Faschang - Optimization of Keyword Grouping in Biomedical Information Retrieval Using Evolutionary Algorithms - 22nd European Modeling and Simulation Symposium EMSS 2010, Fes, Morocco, 2010, pp. 25-30 more
2010
S. M. Winkler, M. Affenzeller, G. K. Kronberger, S. Wagner, W. Jacak, H. Stekel - Feature Selection in the Analysis of Tumor Marker Data Using Evoutionary Algorithms - 22nd European Modeling and Simulation Symposium EMSS 2010, Fes, Morocco, 2010, pp. 1-6 more
2010
S. M. Winkler, S. Auer, M. Affenzeller - Heuristic Modeling of Time Course Data of Patiens Suffering from Alzheimer's Disease - Proceedings of the 4th Symposium of Austrian Universities of Applied Sciences, Pinkafeld, Austria, 2010, pp. 23-28 more
2009
P. Kulczycki, H. Brandstaetter-Mueller, G. Lirk - Bioinformatics Resource Facility Hagenberg—Building High Performance Computing Services for Solving Bioinformatical Problems - Proceedings of 21st European Modeling and Simulation Symposium EMSS 2009, Tenerife, Spain, 2009 more
2009
T. Kern, M. Kommenda, V. Dorfer, J. W. Bauer, K. Oender - PRIMOS: AN INTEGRATED PLATFORM FOR EXPLORING PROTEIN-PROTEIN INTERACTIONS - Proceedings of 21st European Modeling and Simulation Symposium EMSS 2009, Tenerife, Spain, 2009, pp. 6 more
2009
S. M. Winkler, M. Affenzeller, S. Wagner - Fine Grained Population Diversity Analysis for Parallel Genetic Programming - Proceedings of the IEEE International Parallel & Distributed Processing Symposium IPDPS 2009, Roma, Italy, 2009, pp. 8 more
2009
S. M. Winkler, S. Auer, M. Affenzeller, Y. Donabauer, B. Reisberg - Heuristic Modeling of the Mental Progress of Persons with Normal Brain Aging, Subjective Cognitive Impairment, Mild Cognitive Impairment, Alzheimer's Disease and Related Dementia Disorders - Proceedings of 21st European Modeling… more
2009
S. M. Winkler, M. Affenzeller, S. Wagner, G. K. Kronberger - Analysis of Patient Data and Evolutionary Design of Virtual Sensors for Diseases - Proceedings of the 3rd Symposium of Austrian Universities of Applied Sciences, Fachhochschule Kärnten, Villach, Austria, 2009, pp. 56-61 more
2009
C. Frech, K. Breuer, B. Ronacher, T. Kern, C. Sohn, G. Gebauer - hybseek: Pathogen primer design tool for diagnostic multi-analyte assays - COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, Vol. 94, No. 1, 2009, pp. 6 more
2009
S. M. Winkler, M. Affenzeller, S. Wagner - Using Enhanced Genetic Programming Techniques for Evolving Classifiers in the Context of Medical Diagnosis - Genetic Programming and Evolvable Machines, Vol. 10, No. 2, 2009, pp. 111-140 more
2009
M. Affenzeller, S. M. Winkler, S. Wagner, A. Beham - Genetic Algorithms and Genetic Programming - Consortium of Higher Education Researchers, 2009 more
2009
C. Frech, M. Kommenda, V. Dorfer, T. Kern, H. Hintner, J. W. Bauer, K. Oender - Improved Homology-driven Computational Validation of Protein-Protein Interactions Based on Evolutionary Gene Duplication and Divergence Hypothesis - BMC Bioinformatics, Vol. 10, No. 1, 2009, pp. 18 more
2008
S. M. Winkler - Evolutionary System Identification - Modern Concepts and Practical Applications, 2008 more
2008
M. Kommenda, C. Frech, V. Dorfer, T. Kern, J. W. Bauer, K. Oender - Integration and simplification of protein-protein interaction data - Proceedings of FFH2008, Wels, Austria, 2008, pp. 434-438 more
2007
C. Frech - Probabilistic Assessment of Protein-Protein Interaction Confidence by Large-Scale Analysis of Homologous Protein-Protein Interactions - Master/Diploma Thesis, FH OÖ Fakultät Hagenberg, Austria, 2007, pp. 1-109 more
2007
S. M. Winkler, M. Affenzeller, S. Wagner - Advanced Genetic Programming Based Machine Learning - Journal of Mathematical Modelling and Algorithms, Vol. 6, No. 3, 2007, pp. 455-480 more
2007
W. Strasser, D. Siegl, K. Oender, J. W. Bauer - InSilico Proteomics System: Integration and Application of Protein and Protein-Protein Interaction Data using Microsoft .NET in Integrative Bioinformatics (Editors: R. Hofestädt, T. Töpel) - Shaker Verlag, 2007, pp. 75-86 more
2007
W. Strasser, T. Kern, C. Frech, M. Kommenda, J. W. Bauer, K. Oender - Integration and simplification of protein-protein interaction data - ISMB/ECCB 2007 Conference Proceedings, Wien, Austria, 2007, pp. 434-438 more
2006
S. M. Winkler, M. Affenzeller, S. Wagner - Automatic Data Based Patient Classification Using Genetic Programming - Cybernetics and Systems 2006, Wien, Austria, 2006, pp. 251-256 more
2006
S. M. Winkler, M. Affenzeller, S. Wagner - HeuristicModeler: A Multi-Purpose Evolutionary Machine Learning Algorithm and its Applications in Medical Data Analysis - Proceedings of the International Mediterranean Modelling Multiconference (I3M 2015), Barcelona, Spain, 2006, pp. 629-634 more
2005
K. Breuer - Using a Knowledge-based System for Validating and Classifying Requests in Large-scale Laboratories, Considering Preliminary Diagnoses. - Proceedings of FH Science Day 2005, Steyr, Austria, 2005, pp. 7 more
2005
S. M. Winkler, M. Affenzeller, S. Wagner - A Genetic Programming Based Tool for Supporting Bioinformatical Classification Problems - Proceedings of FH Science Day 2005, Steyr, Austria, 2005, pp. 3-10 more
2005
K. Oender, T. Kern, W. Strasser, K. Richter, H. Hintner, J. W. Bauer - The function of the N-terminal domain of TGF-ßII: A systematic genome-wide protein-protein interaction study in human keratinocytes - JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 125, No. 3, 2005, pp. 2 more
2004
K. Oender, T. Kern, W. Strasser, K. Richter, H. Hintner, J. W. Bauer - The actin-ECM (extracellular matrix) linkage defects caused by mutations in the Kindlin1 gene are mediated by actinin alpha in Archives of Dermatological Research (Editors: N. Nescio) - Springer Vieweg, 2004, pp. 1 more
2004
T. Kern, K. Breuer, D. Siegl, W. Strasser - Knowledge-Based Systems for Biomedical Laboratory Applications - Proceedings of 2004 IEEE International Conference on Information Reuse and Integration, Las Vegas, United States of America, 2004, pp. 314-319 more
2015
Chronic diseases often decrease the quality of life and the well-being of patients. The aim of this project is to develop a platform that supports self-help strategies for people with chronic diseases:… more
2013
Within the Regio 13 project "Transplant - markers for humoral and cellular rejection after renal transplantation" (Lead: Blutzentrale of the OÖRK) we research whether and how next-generation… more
2013
2013
Fluorescence microscopy is going to become one of the core technologies for biomedical research and diagnostics. Therefore, image analysis is an increasing challenge for biomedical researchers. In the… more
2013
To identify proteins in biological samples mass spectrometry (MS) is most often applied: proteins are digested to peptides which are subsequently analyzed. Within the last decade, a new generation of mass… more
2012
2011
2011
Receptor proteins on the surface of human cells play a key role in the transmission of signals from the environment into the interior of the cell. A complex network of these proteins controls all cellular… more
2010
In our modern knowledge society, the effective use of mostly unstructured and exponentially growing data is one of the biggest challenges for computer science. Humans as information receivers only have… more
2005
2003
In the past few years, the promises of biotechnology - understanding the human body and its intercellular processes, detailed knowledge of health and disease, better diagnostics and treatments - have been… more