Person

FH-Prof. DI Dr. Jaroslaw Jacak

STED Microscopy and Lithography, Single molecule scanning and analysis techniques, Laser Optics , Fluorescent Microscopy and Spectroscopy, Biotechnology, Biomaterials, Nanolitography

Forschungsinteressen

  • Single molecule scanning and analysis techniques
  • Biomaterials
  • Laser Optics
  • STED Microscopy and Lithography
  • Fluorescent Microscopy and Spectroscopy
  • Biotechnology
  • Nanolitography
2018
B. Buchegger, J. Kreutzer, M. Axmann, S. Mayr, R. Wollhofen, B. Plochberger, J. Jacak, T. Klar - Proteins on Supported Lipid Bilayers Diffusing around Proteins Fixed on Acrylate Anchors - ANALYTICAL CHEMISTRY,… mehr
2018
F. Hauser, S. Mayr, A. Tauscher, J. Jacak - Statistical analysis of 3D localization microscopy data for quantification of protein distribution upon clot formation - Proceedings of 8th Single Molecule Localization… mehr
2018
S. Mayr, F. Hauser, A. Peterbauer, A. Tauscher, C. Naderer, M. Axmann, B. Plochberger, J. Jacak - Localization Microscopy of Actin Cytoskeleton in Human Platelets - International Journal of Molecular Sciences,… mehr
2017
S. Mayr, M. Brodesser, F. Hauser, J. Breuss, M. Aspetsberger, D. M. Borgmann, S. M. Winkler, C. Gabriel, E. Priglinger, J. Jacak, B. Plochberger - A FAST AND RELIABLE ONLINE-SYSTEM FOR PLATELET VIABILITY… mehr
2017
R. Wollhofen, J. Jacak, T. Klar - Two photon laser induced molecular patterning - Proceedings of the XIX Annual Linz Winter Workshop 2017, Linz, Österreich, 2017 mehr
2017
R. Wollhofen, B. Buchegger, J. Jacak, J. Kreutzer, T. Klar - Functional photoresists for sub-diffraction stimulated emission depletion lithography - OPTICAL MATERIALS EXPRESS , Vol. 7, No. 7, 2017, pp.… mehr
2017
C. Plamadeala, R. Wollhofen, J. Jacak, J. Heitz, T. Klar - Bioinspired polymer microstructures for directional transport of oily liquids - Royal Society Open Science, Vol. 10, No. 1098, 2017 mehr
2017
G. Langer, B. Buchegger, J. Jacak, T. Klar, T. Berer - Frequency domain optical resolution photoacoustic and fluorescence microscopy using a modulated laser diode - SPIE BiOS 2017 , San Francisco, Vereinigte… mehr
2017
J. Kreutzer, B. Buchegger, J. Jacak, T. Klar, R. Wollhofen - 3D STED lithography: Protein binding and non-binding - SPIE BiOS 2017 , San Francisco, Vereinigte Staaten von Amerika, 2017 mehr
2017
B. Plochberger, M. Brodesser, F. Hauser, J. Breuss, C. Gabriel, J. Jacak, S. M. Winkler, D. M. Borgmann, A. Hangler, M. Aspetsberger, L. Bindreiter - A Fast and Reliable Online-System for Platelet Viability… mehr
2017
B. Plochberger, M. Brodesser, F. Hauser, M. Axmann, J. Jacak, S. M. Winkler, L. Bindreiter, M. Aspetsberger - A Fast and Reliable Online-System for Platelet Viability Studies - ÖGMBT Meeting 2017, Innsbruck… mehr
2017
S. Mayr, A. Tauscher, F. Hauser, C. Lindner, B. Plochberger, C. Gabriel, H. Stangl, H. Redl, J. Jacak - Three-dimensional nanoscopic visualization of platelet membrane proteins in a white clot in-vitro… mehr
2017
F. Hauser, S. Mayr, B. Buchegger, T. Klar, B. Plochberger, J. Jacak - 3D dSTORM Algorithms Improvement by Application of Geodesic Acceleration - Proceedings of the XIX Annual Linz Winter Workshop 2017,… mehr
2017
B. Buchegger, J. Kreutzer, T. Klar, J. Jacak - Nanostructured functional polymers for selective protein binding - 2017 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference… mehr
2017
J. Jacak, T. Klar, J. Kreutzer, R. Wollhofen - Sub-Diffraction STED Lithography using Orthogonally Functionalized Resins - BIOPHYSICAL JOURNAL, Vol. 112, No. 3, 2017 mehr
2017
M. Axmann, R. Wollhofen, P. Freudenthaler, C. Gabriel, T. Klar, J. Jacak - Multiphoton Polymerized 3D Protein Assay -  ACS Applied Materials & Interfaces, Vol. 10, No. 2, 2017, pp. 10-18 mehr
2016
B. Buchegger, J. Kreutzer, B. Plochberger, R. Wollhofen, J. Jacak, G. Schütz, U. Schubert, T. Klar - Stimulated Emission Depletion Lithography with Mercapto-Functional Polymers - ACS Nano, Vol. 1021,… mehr
2016
B. Aekbote, T. Fekete, J. Jacak, G. Vizsnyiczai, P. Ormos, L. Kelemen - Surface-modified complex SU-8 microstructures for indirect optical manipulation of single cells - Biomedical Optics Express, Vol.… mehr
2016
J. Jacak, R. Wollhofen, T. Klar - Functional polymer scaffolds for biomolecule immobilization - SPIE Photonics Europe Proc., Brüssel, Belgien, 2016, pp. 1-6 mehr
2016
J. Jacak, R. Wollhofen, T. Klar - STED lithography for applications in biology - Proc. Photonics West Conference 9759 (Advanced Fabrication Technologies for Micro/Nano Optics and Photonics), San Francisco,… mehr
2016
G. Langer, B. Buchegger, J. Jacak, T. Berer - Frequency domain photoacoustic and fluorescence microscopy - Biomedical Optics Express, Vol. 7, No. 2692, 2016, pp. 37-43 mehr
2016
J. Jacak, R. Wollhofen, T. Klar - Nanoscopic structuring with STED lithography - SPIE Photonics Europe Proc., Brüssel, Belgien, 2016 mehr
2016
J. Heitz, M. Wiesbauer, R. Wollhofen, J. Jacak, T. Klar - Three-dimensional photonic structures on transparent substrates fabricated by two-photon polymerization for use as cell substrates and for wetting… mehr
2016
S. Mayr, D. M. Borgmann, H. Polin, S. Schaller, T. Endmayr, L. Obritzberger, V. Dorfer, C. Gabriel, S. M. Winkler, J. Jacak - Classification of Rhesus D Antigen Expression at Single Molecule Level by High-Resolution… mehr
2016
J. Heitz, C. Plamadeala, M. Wiesbauer, R. Wollhofen, J. Jacak, T. Klar - Bone-forming cells with pronounced spread into the third dimension in polymer scaffolds fabricated by two-photon polymerization… mehr
2016
B. Plochberger, M. Brodesser, F. Hauser, S. Mayr, J. Jacak, D. M. Borgmann, S. M. Winkler, L. Bindreiter, A. Hangler, M. Aspetsberger - Blood cell viability study via real-time image analysis exemplified… mehr
2016
J. Jacak, R. Wollhofen, T. Klar - Nano-Confined Polymer Structures for Protein Binding - BIOPHYSICAL JOURNAL, Vol. 110, No. 3, 2016 mehr
2016
B. Plochberger, R. Wollhofen, J. Jacak, M. Axmann, G. Schütz, T. Klar - Confinement of Lipid Membranes by Nanostructured Polymer Patterns for Cell to Cell Mimicking - BIOPHYSICAL JOURNAL, Vol. 110, No.… mehr
2015
T. Klar, B. Buchegger, R. Wollhofen, J. Jacak - STED-Lithography for Bio-Applications - Proc. CLEO/Europe - EQEC 2015, München, Deutschland, 2015, pp. 1-6 mehr
2015
J. Jacak, S. Schaller, D. M. Borgmann, S. M. Winkler - Characterization of the Distance Relationship Between Localized Serotonin Receptors and Glia Cells on Fluorescence Microscopy Images of Brain Tissue… mehr
2015
S. M. Winkler, S. Schaller, D. M. Borgmann, V. Dorfer, M. Affenzeller, J. Jacak, H. Redl, J. Weghuber - Identification and classification of objects and motions in microscopy images of biological samples… mehr
2015
R. Wollhofen, J. Jacak, T. Klar - Laser induced protein patterning - DK nanocell Summerschool Proceedings, Strobl, Österreich, 2015 mehr
2015
S. Puthukodan, J. Jacak, R. Wollhofen, T. Klar - Stimulated Emission Depletion Microscopy - DK nanocell Summerschool Proceedings, Strobl, Österreich, 2015 mehr
2015
R. Wollhofen, B. Buchegger, J. Jacak, M. Wiesbauer, T. Klar - Sub 100 nm STED Lithography - DINAMO (Discussions on Nano & Mesoscopic Optics) 2015, El Chalten, Argentinien, 2015 mehr
2015
D. M. Borgmann, S. Mayr, H. Polin, L. Obritzberger, S. Schaller, V. Dorfer, J. Jacak, S. M. Winkler - Classifying Human Blood Samples Using Characteristics of Single Molecules and Cell Structures on Microscopy… mehr
2015
B. Buchegger, J. Kreutzer, J. Jacak, B. Plochberger, R. Wollhofen, U. Schubert, G. Schütz, T. Klar - STED-Lithography with Mercapto-Functional Polymers - ACS Nano, Vol. 10, No. 9, 2015 mehr
2014
J. Jacak, M. Sams, L. Muresan, R. Silye, K. Schilcher - Spatial cluster analysis of nanoscopically mapped serotonin receptors for classification of fixed brain tissue - Journal of Biomedical Optics, Vol.… mehr
2014
R. Wollhofen, B. Buchegger, J. Jacak, T. Klar - Nano-Confined Polymer Structures for Adhesive Protein Binding - European Optical Society EOSAM 2014 Proc., Berlin, Deutschland, 2014 mehr
2014
J. Jacak, T. Klar, M. Wiesbauer, R. Wollhofen - Nano-confined polymer structures for protein adhesion - Proc. 2014 Photonics West Conference, San Francisco, Vereinigte Staaten von Amerika, 2014 mehr
2014
J. Jacak - STED Lithography Structuring with Functional Clusters - Proceedings of XXVth IUPAC Symposium on Photochemistry, Bordeaux, Frankreich, 2014, pp. 2-7 mehr
2014
J. Jacak, J. Göhring, N. Fulcher, A. Barta - Suitable transfection methods for single particle tracing in plant suspension cells - Plant Methods, Vol. 10, No. 1, 2014 mehr
2014
J. Göhring, J. Jacak, A. Barta - Imaging of Endogenous Messenger RNA Splice Variants in Living Cells Reveals Nuclear Retention of Transcripts Inaccessible to Nonsense-Mediated Decay in Arabidopsis -… mehr
2013
J. Jacak, M. Wiesbauer, R. Wollhofen, T. Klar - Nano-confined Protein Anchors - Proceedings European Conferences on Biomedical Optics (ECBO) 2013, München, Deutschland, 2013 mehr
2013
J. Jacak, R. Wollhofen, T. Klar, M. Wiesbauer - Nano-confined protein anchors, structured by STED lithography, probed by dSTORM - Proc. DPG-Frühjahrstagung der Sektion Kondensierte Materie (SKM), Regensburg,… mehr
2013
J. Jacak, R. Wollhofen, T. Klar - Nano resolution and 55nm line width achieved in visible light STED-lithography - The European Conference on Lasers and Electro-Optics, Munich, Deutschland, 2013 mehr
2013
R. Wollhofen, J. Jacak, M. Wiesbauer, T. Klar - Applications of sub 100 nm STED Lithography in Nano- and Biophotonics - Proceedings EOS Topical Meeting on Optics at the Nanoscale (ONS'13), Capri, Italien,… mehr
2013
J. Jacak, C. Hrelescu, J. Heitz - Applications of Laser-Induced Periodic Surface Structures (LIPSS): Formation of Gold Nano- Wires and Activation of Biological Cells, Cultivated on Polymer Substrates … mehr
2013
J. Jacak, R. Wollhofen - Single Molecule Spectroscopy - SPIE BiOS 2013, San Francisco, Vereinigte Staaten von Amerika, 2013 mehr
2013
S. Schaller, J. Jacak, M. Sams, S. M. Winkler - Statistical Analysis of the Relationship between Spots and Structures in Microscopy Images - Lecture Notes in Computer Science LNCS 8111, Las Palmas de Gran… mehr
2013
S. Schaller, J. Jacak, P. Bettelheim, D. Gschwandtner, S. M. Winkler - Analyzing Motion Characteristics of Single Molecules for Providing Evidence of PNH in Microscopy Images - Proceedings of the 21st… mehr
2013
S. Schaller, J. Jacak, D. Gschwandtner, P. Bettelheim, S. M. Winkler - Identification of PNH Affected Cells by Classifying Motion Characteristics of Single Molecules - Proceedings of the International… mehr
2013
J. Jacak, S. Schaller, M. Sams, D. M. Borgmann, R. Silye, S. M. Winkler - Spatial Analysis Approach for the Classification of Localization Microscopy Images - Linz Winter School 2013, Linz, Österreich,… mehr
2013
J. Göhring, J. Jacak, N. Fulcher - TeloTool: A New Tool for Telomere Length Measurement from Terminal Restriction Fragment (TRF) Analysis with Improved Probe Intensity - NUCLEIC ACIDS RESEARCH, Vol. 42,… mehr
2013
J. Jacak, M. Wiesbauer, R. Wollhofen, B. Vasic, K. Schilcher, T. Klar - Nano-Anchors with Single Protein Capacity Produced with STED Lithography - Nano Letters , Vol. 13, No. 11, 2013 mehr
2013
R. Wollhofen, J. Jacak, J. Katzmann, C. Hrelescu, T. Klar - 120 nm resolution and 55 nm structure size in STED-lithography - Optics Express, Vol. 21, No. 9, 2013 mehr
2013
J. Jacak, H. Schnidar, L. Muresan, F. Aberger, G. Schütz, J. Hesse - Expression analysis of multiple myeloma cancer stem cells using single molecule microarray readout - JOURNAL OF BIOTECHNOLOGY, Vol.… mehr
2012
S. Schaller, J. Jacak, D. M. Borgmann, J. Weghuber, S. M. Winkler - An Image Analysis Suite for Automated Spot Detection in Cellular and Nano Structures of Microscopy Images - Proceedings of the 20th Annual… mehr
2012
J. Jacak, Z. Szegletes, P. Ormos, G. Schütz - Aminosilane-based functionalization of two-photon polymerized SU-8 microstructures - EUROPEAN POLYMER JOURNAL, Vol. 48, No. 10, 2012 mehr
2012
D. Borgmann, J. Weghuber, S. Schaller, J. Jacak, S. M. Winkler - Identification of Patterns in Microscopy Images of Biological Samples using Evolution Strategies - Proceedings of the 24th European Modeling… mehr
2012
S. Schaller, S. M. Winkler, J. Weghuber, M. Sams, J. Jacak - µDetect: Design of a Framework for Optimized Structure Analysis in Fluorescence Microscopy Images - Tagungsband des 6. Forschungsforums der… mehr
2011
R. Schmidt, J. Jacak, C. Schirwitz, V. Stadler, G. Schütz - Single-molecule detection on a protein-array assay platform for detection of a tuberculosis antigen - Journal of Proteome Research, Vol. 10,… mehr
2010
J. Jacak, C. Hesch, J. Hesse, G. Schütz - Identification of immobile single molecules using polarization- modulated asynchronous time delay and integration-mode scanning - ANALYTICAL CHEMISTRY, Vol. 82,… mehr
2010
J. Jacak, L. Muresan, J. Hesse, E. Klement, G. Schütz - Microarray analysis at single molecule resolution - IEEE transactions on nanobioscience , Vol. 9, No. 1, 2010 mehr
2009
J. Jacak, J. Hesse, C. Hesch, G. Schütz - Two-Stage Focus Hold System for Rapid Ultrasensitive Readout of Large Area Biochips - JOURNAL OF MICROSCOPY-OXFORD, Vol. 234, No. 3, 2009 mehr
2009
J. Jacak, J. Hesse, L. Muresan, F. Aberger, G. Schütz - Oligonucleotide Microarray Analysis with Single Molecule Sensitivity - BIOPHYSICAL JOURNAL, Vol. 96, No. 3, 2009 mehr
2007
B. Plochberger, M. Brodesser, F. Hauser, J. Jacak, S. M. Winkler, D. M. Borgmann, S. Mayr, J. Breuss, C. Gabriel, A. Hangler, M. Aspetsberger, L. Bindreiter - Blood cell viability study via real-time image… mehr
2006
J. Hesse, J. Jacak, S. Howorka, L. Muresan, F. Aberger, G. Schütz - RNA expression profiling at the single molecule level - GENOME RESEARCH, Vol. 16, No. 8, 2006 mehr
2005
J. Jacak, J. Hesse, C. Hesch, F. Aberger, S. Howorka, G. Schütz - Ultra–sensitive DNA detection on microarrays” - Proceedings of SPIE, Vol. 5699, No. 1, 2005 mehr
2004
J. Hesse, J. Jacak, A. Sonnleitner, O. Höglinger, G. Schütz - Single molecule reader for high-throughput bioanalysis - ANALYTICAL CHEMISTRY, Vol. 76, No. 19, 2004 mehr
2016
Im Rahmen dieses von der Europäischen Union geförderten, interregionalen Projekts Czech-Austrian-Center for Supracellular Medical Research wurde eine neue Einrichtung zur Herstellung von Blutgefäßen… mehr
2016
Biomimetische Materialien zielen darauf ab sowohl Struktur wie auch Funktion biologischer Materialien zu imitieren. Im Fokus des Projektes stehen strukturierte Polymeroberflächen im Mikro- bis Nanometerbereich,… mehr
2014
Das adaptive Immunsystem (in erster Linie repräsentiert durch B- und T-Zellen) spielt eine lebenswichtige Rolle bei der Erkennung von potenziellen Krankheitserregern, wie z.B. pathogenen Mikroorganismen… mehr
2013
Fluorescence microscopy is going to become one of the core technologies for biomedical research and diagnostics. Therefore, image analysis is an increasing challenge for biomedical researchers. In the… mehr
2011
Rezeptor-Proteine auf der Oberfläche von menschlichen Zellen spielen eine Schlüsselrolle bei der Weiterleitung von Signalen aus der Umgebung in das Innere der Zelle. Ein komplexes Netzwerk dieser… mehr
2010
Ziel des Projektes ist der Aufbau von technologischen Plattformen basierend auf hochauflösenden mikroskopischen Techniken zur Untersuchung und Analyse von Proteinexpressionen für Anwendungen… mehr